HFE anticorps (N-Term)

N° du produit ABIN2781799

L’anticorps Lapin Polyclonal anti-HFE a été validé pour WB. Il convient pour détecter HFE dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval et Lapin.

Aperçu rapide pour HFE anticorps (N-Term) (ABIN2781799)

Antigène: HFE (Hemochromatosis (HFE))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HFE est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HFE anticorps

Épitope: N-Term

Séquence: MGASEQDLGL SLFEALGYVD DQLFVFYDHE SRRVEPRTPW VSSRISSQMW

Homologie: Cow: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against HFE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HFE

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 348 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HFE

Antigène: HFE (Hemochromatosis (HFE))

Autre désignation: HFE

Sujet: HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
Alias Symbols: HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1, MVCD7, TFQTL2
Protein Interaction Partner: B2M, SYVN1, UBC, TFR2, TFRC,
Protein Size: 348

Poids moléculaire: 40 kDa

ID gène: 3077

NCBI Accession: NM_000410, NP_000401

UniProt: Q30201

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process