Tyrosinase-Related Protein 1 anticorps (Middle Region)

N° du produit ABIN2781815

Cet anticorps Lapin Polyclonal détecte spécifiquement Tyrosinase-Related Protein 1 dans IHC et WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Chévre, Cheval, Lapin, Mouton, Boeuf (Vache), Cobaye et Poisson zèbre (Danio rerio) et a été mentionné dans 1 publication.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (Middle Region) (ABIN2781815)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain, Souris, Rat, Chien, Chévre, Cheval, Lapin, Mouton, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Épitope: Middle Region

Séquence: NDPIFVLLHT FTDAVFDEWL RRYNADISTF PLENAPIGHN RQYNMVPFWP

Homologie: Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TYRP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TYRP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 537 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Tyrosinase-Related Protein 1 (ABIN2781815)

Horibe, Satoh, Shiota, Kumagai, Horike, Takemori, Uesato, Sugie, Obata, Kawahara, Nagaoka: "Induction of melanogenesis by 4'-O-methylated flavonoids in B16F10 melanoma cells." dans: Journal of natural medicines, Vol. 67, Issue 4, pp. 705-10, (2013) (PubMed).

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: TYRP1

Sujet: TYRP1 catalyses the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. It may regulate or influence the type of melanin synthesized.
Alias Symbols: CAS2, CATB, GP75, TRP, TYRP, b-PROTEIN
Protein Interaction Partner: RAB11A, TF, RAB5A, HSPA4, TYR, GIPC1,
Protein Size: 537

Poids moléculaire: 61 kDa

ID gène: 7306

NCBI Accession: NM_000550, NP_000541

UniProt: P17643