MTUS1 anticorps (Middle Region)

N° du produit ABIN2781855

Cet anticorps Lapin Polyclonal détecte spécifiquement MTUS1 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Lapin et Boeuf (Vache).

Aperçu rapide pour MTUS1 anticorps (Middle Region) (ABIN2781855)

Antigène: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTUS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MTUS1 anticorps

Épitope: Middle Region

Séquence: KRLSMENEEL LWKLHNGDLC SPKRSPTSSA IPLQSPRNSG SFPSPSISPR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MTUS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MTUS1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1270 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MTUS1

Antigène: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Autre désignation: MTUS1

Sujet: MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
Alias Symbols: ATIP, DKFZp586D1519, DKFZp686F20243, FLJ14295, KIAA1288, MP44, MTSG1, ATBP
Protein Interaction Partner: UBC, MMS19, ORC4, Ptpn6, MTUS1, AGTR2,
Protein Size: 1270

Poids moléculaire: 141 kDa

ID gène: 57509

NCBI Accession: NM_001001924, NP_001001924

UniProt: Q9ULD2