LCLAT1 anticorps (Middle Region)

N° du produit ABIN2781857

L’anticorps Lapin Polyclonal anti-LCLAT1 a été validé pour WB. Il convient pour détecter LCLAT1 dans des échantillons de Souris, Humain, Rat, Lapin, Boeuf (Vache), Chien, Cobaye et Cheval. Il y a 1 publication disponible.

Aperçu rapide pour LCLAT1 anticorps (Middle Region) (ABIN2781857)

Antigène: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Reactivité: Souris, Humain, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LCLAT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LCLAT1 anticorps

Épitope: Middle Region

Séquence: YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LYCAT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 376 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-LCLAT1 (ABIN2781857)

Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." dans: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

Détails sur LCLAT1

Antigène: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Autre désignation: LYCAT

Sujet: LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
Protein Interaction Partner: LNX1, GOPC, RNF2, UBC, ELAVL1,
Protein Size: 376

Poids moléculaire: 44 kDa

ID gène: 253558

NCBI Accession: NM_001002257, NP_001002257

UniProt: Q6UWP7