LCLAT1 anticorps (Middle Region)

N° du produit ABIN2781857

Il existe 1 publication pour ce produit. L’anticorps anti-LCLAT1 Polyclonal Lapin est utilisé pour la détection de LCLAT1 dans des échantillons de Humain, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval et Rat. Il a été validé pour WB.

Aperçu rapide pour LCLAT1 anticorps (Middle Region) (ABIN2781857)

Antigène: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Reactivité: Humain, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LCLAT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LCLAT1 anticorps

Épitope: Middle Region

Fonction: LYCAT Antibody - middle region

Séquence: YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LYCAT

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44426-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-LCLAT1 (ABIN2781857)

Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." dans: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

Détails sur LCLAT1

Antigène: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Autre désignation: LYCAT

Sujet:

Background Information: LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.

Gene Name: Lysocardiolipin acyltransferase 1

Alternative Symbols: LYCAT, AGPAT8, ALCAT1, 1AGPAT8, UNQ1849, HSRG1849

Protein Name: cDNA FLJ61482, highly similar to Homo sapiens lysocardiolipin acyltransferase (LYCAT), transcript variant 1, mRNA EMBL BAG63827.1

Poids moléculaire: 44kDa

ID gène: 253558

NCBI Accession: NP_001002257

UniProt: Q6UWP7