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CCDC90A anticorps (Middle Region)

MCUR1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782009
  • Antigène Voir toutes CCDC90A (MCUR1) Anticorps
    CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))
    Épitope
    • 15
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye
    Hôte
    • 20
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CCDC90A est non-conjugé
    Application
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    ELHQLKQQVM DEVIKVRTDT KLDFNLEKSR VKELYSLNEK KLLELRTEIV
    Homologie
    Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against CCDC90A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human CCDC90A
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 359 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Shanmughapriya, Rajan, Hoffman, Zhang, Guo, Kolesar, Hines, Ragheb, Jog, Caricchio, Baba, Zhou, Kaufman, Cheung, Kurosaki, Gill, Madesh: "Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU." dans: Science signaling, Vol. 8, Issue 366, pp. ra23, (2015) (PubMed).

    Mallilankaraman, Cárdenas, Doonan, Chandramoorthy, Irrinki, Golenár, Csordás, Madireddi, Yang, Müller, Miller, Kolesar, Molgó, Kaufman, Hajnóczky, Foskett, Madesh: "MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism." dans: Nature cell biology, Vol. 14, Issue 12, pp. 1336-43, (2012) (PubMed).

    Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

    Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." dans: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).

  • Antigène
    CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))
    Autre désignation
    CCDC90A (MCUR1 Produits)
    Synonymes
    anticorps C6orf79, anticorps CCDC90A, anticorps 6230416A05Rik, anticorps AU015498, anticorps AV136929, anticorps AW554392, anticorps C88263, anticorps Ccdc90a, anticorps RGD1307673, anticorps mitochondrial calcium uniporter regulator 1, anticorps mitochondrial calcium uniporter regulator 1 L homeolog, anticorps MCUR1, anticorps Mcur1, anticorps mcur1.L
    Sujet
    Essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
    Alias Symbols: C6orf79, FLJ20958, CCDC90A
    Protein Size: 359
    Poids moléculaire
    40 kDa
    ID gène
    63933
    NCBI Accession
    NM_001031713, NP_001026883
    UniProt
    Q96AQ8
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