CCDC90A anticorps (Middle Region)

N° du produit ABIN2782009

Cet anticorps Lapin Polyclonal détecte spécifiquement CCDC90A dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval et Cobaye. Il a été cité dans 4+ publications.

Aperçu rapide pour CCDC90A anticorps (Middle Region) (ABIN2782009)

Antigène: CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC90A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCDC90A anticorps

Épitope: Middle Region

Fonction: CCDC90A Antibody - middle region

Séquence: ELHQLKQQVM DEVIKVRTDT KLDFNLEKSR VKELYSLNEK KLLELRTEIV

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CCDC90A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CCDC90A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44777-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CCDC90A (ABIN2782009)

Shanmughapriya, Rajan, Hoffman, Zhang, Guo, Kolesar, Hines, Ragheb, Jog, Caricchio, Baba, Zhou, Kaufman, Cheung, Kurosaki, Gill, Madesh: "Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU." dans: Science signaling, Vol. 8, Issue 366, pp. ra23, (2015) (PubMed).

Mallilankaraman, Cárdenas, Doonan, Chandramoorthy, Irrinki, Golenár, Csordás, Madireddi, Yang, Müller, Miller, Kolesar, Molgó, Kaufman, Hajnóczky, Foskett, Madesh: "MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism." dans: Nature cell biology, Vol. 14, Issue 12, pp. 1336-43, (2012) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." dans: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).

Détails sur CCDC90A

Antigène: CCDC90A (MCUR1) (Mitochondrial Calcium Uniporter Regulator 1 (MCUR1))

Autre désignation: CCDC90A

Sujet:

Background Information: Essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.

Gene Name: Coiled-coil domain containing 90A

Alternative Symbols: FMP32, C6orf79, CCDC90A

Protein Name: Coiled-coil domain-containing protein 90A, mitochondrial

Poids moléculaire: 40kDa

ID gène: 63933

NCBI Accession: NP_001026883

UniProt: Q96AQ8