NrCAM anticorps (N-Term)

N° du produit ABIN2782029

Détail du produit anti-NrCAM anticorps

Antigène: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Épitope: N-Term

Reactivité: Souris, Humain, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NrCAM est non-conjugé

Application: Western Blotting (WB)

Séquence: PLILFLCQMI SALEVPLDLV QPPTITQQSP KDYIIDPREN IVIQCEAKGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NRCAM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NRCAM

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 771 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NrCAM

Antigène: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Autre désignation: NRCAM (NRCAM Produits)

Synonymes: anticorps CD56, anticorps MSK39, anticorps NCAM, anticorps Bravo, anticorps C030017F07Rik, anticorps C130076O07Rik, anticorps mKIAA0343, anticorps NRCAM, anticorps si:dkey-240a12.1, anticorps Nr-CAM, anticorps neural cell adhesion molecule 1, anticorps neuronal cell adhesion molecule, anticorps neuronal cell adhesion molecule L homeolog, anticorps neuronal cell adhesion molecule a, anticorps NCAM1, anticorps NRCAM, anticorps Nrcam, anticorps nrcam.L, anticorps nrcama, anticorps nrcam

Sujet: Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.
Alias Symbols: KIAA0343, MGC138845, MGC138846
Protein Interaction Partner: LNX1, MAGI3, HSPA12A, MACF1, UBC, NFASC, NRCAM, CNTN2, PTPRB, ANK2,
Protein Size: 771

Poids moléculaire: 84 kDa

ID gène: 4897

NCBI Accession: NM_001037132

UniProt: Q4KMQ7

Pathways: Regulation of Cell Size