POMT1 anticorps (Middle Region)

N° du produit ABIN2782091

Détail du produit anti-POMT1 anticorps

Antigène: POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Porc, Rat, Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POMT1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LTFQILLLPV VLQHISDHLC RSQLQRSIFS ALVVAWYSSA CHVSNTLRPL

Homologie: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 77%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against POMT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human POMT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 725 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POMT1

Antigène: POMT1 (Protein-O-Mannosyltransferase 1 (POMT1))

Autre désignation: POMT1 (POMT1 Produits)

Synonymes: anticorps LGMD2K, anticorps MDDGA1, anticorps MDDGB1, anticorps MDDGC1, anticorps RT, anticorps AI505244, anticorps protein O-mannosyltransferase 1, anticorps protein-O-mannosyltransferase 1, anticorps POMT1, anticorps Pomt1

Sujet: POMT1 is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K).O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. POMT1 shares sequence similarity with protein O-mannosyltransferases of S. cerevisiae. In yeast, these enzymes are located in the endoplasmic reticulum (ER) and are required for cell integrity and cell wall rigidity. POMT1 also shows similarity to the Drosophila 'rotated abdomen' (rt) gene, which when mutated causes defects in myogenesis and muscle structure.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB154785.1 1-42 43-2420 AK074874.1 1-2378 2421-2617 BF984005.1 438-634 2618-3080 AL358781.19 127610-128072
Alias Symbols: FLJ37239, LGMD2K, RT, MDDGA1, MDDGB1, MDDGC1
Protein Interaction Partner: UBC, POMT2,
Protein Size: 725

Poids moléculaire: 82 kDa

ID gène: 10585

NCBI Accession: NM_001077365, NP_001070833

UniProt: B3KQG0