KTN1 anticorps (Middle Region)

N° du produit ABIN2782098

Détail du produit anti-KTN1 anticorps

Antigène: KTN1 (Kinectin 1 (Kinesin Receptor) (KTN1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KTN1 est non-conjugé

Application: Western Blotting (WB)

Séquence: EELLKVISER EKEISGLWNE LDSLKDAVEH QRKKNNDLRE KNWEAMEALA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against KTN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KTN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1306 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KTN1

Antigène: KTN1 (Kinectin 1 (Kinesin Receptor) (KTN1))

Autre désignation: KTN1 (KTN1 Produits)

Sujet: Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin, an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CG1, KIAA0004, KNT, MGC133337, MU-RMS-40.19
Protein Interaction Partner: SYNE4, CLEC7A, SGTA, MEOX2, BNIP3, UBC, MDM2, BMI1, CTPS2, EHD1, WARS, HEXA, NPM1, CDH2, NEURL4, HERC2, ARRB1, SUMO2, SUMO1, PLEKHA5, PSMD7, KIF5B, IKBKE, RAC1, RHOG, RHOA, EEF1D, CDC42, AKT1,
Protein Size: 1306

Poids moléculaire: 150 kDa

ID gène: 3895

NCBI Accession: NM_001079522, NP_001072990

UniProt: Q17RZ5