AOC2 anticorps (Middle Region)

N° du produit ABIN2782114

Cet anticorps Lapin Polyclonal détecte spécifiquement AOC2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Rat et Porc.

Aperçu rapide pour AOC2 anticorps (Middle Region) (ABIN2782114)

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AOC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AOC2 anticorps

Épitope: Middle Region

Fonction: AOC2 Antibody - middle region

Séquence: QATMVDIHIL VGKGAVQLLP GAVCVFEEAQ GLPLRRHHNY LQNHFYGGLA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 100%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against AOC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human AOC2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45055-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur AOC2

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Autre désignation: AOC2

Sujet:

Background Information: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine.Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.

Gene Name: Amine oxidase, copper containing 2 (retina-specific)

Alternative Symbols: RAO, DAO2, SSAO

Protein Name: Retina-specific copper amine oxidase

Poids moléculaire: 84kDa

ID gène: 314

NCBI Accession: NP_033720

UniProt: O75106