IL-10RA anticorps (N-Term)
-
- Antigène Voir toutes IL-10RA (IL10RA) Anticorps
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
-
Épitope
- N-Term
-
Reactivité
- Humain, Rat, Boeuf (Vache), Cheval, Chien, Cobaye
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp IL-10RA est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- GSVNLEIHNG FILGKIQLPR PKMAPANDTY ESIFSHFREY EIAIRKVPGN
- Homologie
- Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 85%, Human: 100%, Rat: 77%
- Attributs du produit
- This is a rabbit polyclonal antibody against IL10RA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL10RA
- Top Product
- Discover our top product IL10RA Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 578 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- Autre désignation
- IL10RA (IL10RA Produits)
- Synonymes
- anticorps IL10R1, anticorps IL10RA, anticorps CD210, anticorps CD210a, anticorps CDW210A, anticorps HIL-10R, anticorps IL-10R1, anticorps IL10R, anticorps AW553859, anticorps CDw210, anticorps CDw210a, anticorps Il10r, anticorps mIL-10R, anticorps interleukin 10 receptor subunit alpha, anticorps interleukin 10 receptor, alpha, anticorps IL10RA, anticorps Il10ra
- Sujet
-
IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Alias Symbols: CDW210A, HIL-10R, IL-10R1, IL10R, CD210, CD210a
Protein Interaction Partner: BTRC, UBC, IL10RB, JAK1, IL10,
Protein Size: 578 - Poids moléculaire
- 61 kDa
- ID gène
- 3587
- NCBI Accession
- NM_001558, NP_001549
- UniProt
- Q13651
- Pathways
- Growth Factor Binding
-