Desmoglein 2 anticorps (N-Term)

N° du produit ABIN2782147

L’anticorps Lapin Polyclonal anti-Desmoglein 2 a été validé pour WB et IHC. Il convient pour détecter Desmoglein 2 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Cobaye, Cheval et Lapin. Il y a 1 publication disponible.

Aperçu rapide pour Desmoglein 2 anticorps (N-Term) (ABIN2782147)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Desmoglein 2 anticorps

Épitope: N-Term

Séquence: KIHSDLAEER GLKITYKYTG KGITEPPFGI FVFNKDTGEL NVTSILDREE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DSG2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DSG2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Desmoglein 2 (ABIN2782147)

Hummitzsch, Irving-Rodgers, Hatzirodos, Bonner, Sabatier, Reinhardt, Sado, Ninomiya, Wilhelm, Rodgers: "A new model of development of the mammalian ovary and follicles." dans: PLoS ONE, Vol. 8, Issue 2, pp. e55578, (2013) (PubMed).

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: DSG2

Sujet: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. DSG2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037, CMD1BB
Protein Interaction Partner: UBC, SART3, EED, ADRB2, PAN2, CHCHD2, PLIN3, Trim69, Cbx1, RYK, PKP3, PKP2, JUP, DSC2, DSC1,
Protein Size: 1118

Poids moléculaire: 114 kDa

ID gène: 1829

NCBI Accession: NM_001943, NP_001934

UniProt: Q14126

Pathways: Cell-Cell Junction Organization