FVT1 anticorps (N-Term)
Aperçu rapide pour FVT1 anticorps (N-Term) (ABIN2782154)
Antigène
Voir toutes FVT1 (KDSR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- KKEIEMHSIN DKQVVLCISV DVSQDYNQVE NVIKQAQEKL GPVDMLVNCA
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against KDSR. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of human KDSR
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FVT1 (KDSR) (3-Ketodihydrosphingosine Reductase (KDSR))
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Autre désignation
- KDSR
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Sujet
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The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
Alias Symbols: DHSR, FVT1, SDR35C1
Protein Size: 268 -
Poids moléculaire
- 29 kDa
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ID gène
- 2531
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NCBI Accession
- NM_002035, NP_002026
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UniProt
- B4DMX0
Antigène
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