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GZMK anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-GZMK a été validé pour WB. Il convient pour détecter GZMK dans des échantillons de Humain, Porc et Cheval.
N° du produit ABIN2782156

Aperçu rapide pour GZMK anticorps (N-Term) (ABIN2782156)

Antigène

Voir toutes GZMK Anticorps
GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivité

  • 57
  • 24
  • 16
  • 2
Humain, Porc, Cheval

Hôte

  • 51
  • 13
Lapin

Clonalité

  • 53
  • 11
Polyclonal

Conjugué

  • 30
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp GZMK est non-conjugé

Application

  • 42
  • 22
  • 15
  • 14
  • 11
  • 9
  • 9
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    PTVVLGAHSL SKNEASKQTL EIKKFIPFSR VTSDPQSNDI MLVKLQTAAK

    Homologie

    Horse: 79%, Human: 100%, Pig: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against GZMK. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human GZMK
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 264 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

    Autre désignation

    GZMK

    Sujet

    GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
    Alias Symbols: TRYP2
    Protein Interaction Partner: SET, HMGB2, APEX1, PNKP, LIG4, HNRNPK, GOLGA2, ACTG1, TUBB3, NPLOC4, VCP, UFD1L,
    Protein Size: 264

    Poids moléculaire

    26 kDa

    ID gène

    3003

    NCBI Accession

    NM_002104, NP_002095

    UniProt

    P49863
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