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GZMK anticorps (N-Term)

L’anticorps anti-GZMK Polyclonal Lapin est utilisé pour la détection de GZMK dans des échantillons de Humain, Porc et Cheval. Il a été validé pour WB.
N° du produit ABIN2782156
534,11 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour GZMK anticorps (N-Term) (ABIN2782156)

Antigène

Voir toutes GZMK Anticorps
GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivité

Humain, Porc, Cheval

Hôte

  • 61
  • 13
Lapin

Clonalité

  • 63
  • 11
Polyclonal

Conjugué

  • 30
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp GZMK est non-conjugé

Application

  • 41
  • 24
  • 17
  • 13
  • 11
  • 11
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Épitope

    • 16
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    Fonction

    GZMK Antibody - N-terminal region

    Séquence

    PTVVLGAHSL SKNEASKQTL EIKKFIPFSR VTSDPQSNDI MLVKLQTAAK

    Homologie

    Horse: 79%, Human: 100%, Pig: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against GZMK. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human GZMK
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45219-100UG

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    prevent freeze-thaw cycles

    Stock

    4 °C,-20 °C

    Stockage commentaire

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

    Autre désignation

    GZMK

    Sujet

    Background Information: GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

    Gene Name: Granzyme K (granzyme 3, tryptase II)

    Alternative Symbols: TRYP2

    Protein Name: Granzyme K

    Poids moléculaire

    26kDa

    ID gène

    3003

    NCBI Accession

    NP_002095

    UniProt

    P49863
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