Lamin B Receptor anticorps (Middle Region)

N° du produit ABIN2782167

Détail du produit anti-Lamin B Receptor anticorps

Antigène: Lamin B Receptor (LBR)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Porc, Lapin, Saccharomyces cerevisiae, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B Receptor est non-conjugé

Application: Western Blotting (WB)

Séquence: GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Yeast: 77%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against LBR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LBR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 615 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Lamin B Receptor

Antigène: Lamin B Receptor (LBR)

Autre désignation: LBR (LBR Produits)

Synonymes: anticorps CG17952, anticorps Dmel\\CG17952, anticorps dLBR, anticorps sb:cb406, anticorps zgc:86649, anticorps wu:fb75h08, anticorps wu:fc47b04, anticorps wu:fd36b07, anticorps lbr-A, anticorps Xp58, anticorps p58 gene, anticorps LBR, anticorps DHCR14B, anticorps LMN2R, anticorps PHA, anticorps TDRD18, anticorps AI505894, anticorps ic, anticorps Nbp60, anticorps lamin B receptor, anticorps Lamin B receptor, anticorps lamin B receptor S homeolog, anticorps LBR, anticorps lbr, anticorps lbr.S, anticorps Lbr

Sujet: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Alias Symbols: DHCR14B, LMN2R, MGC9041, PHA
Protein Interaction Partner: UBC, EED, CLK3, HIPK4, LMNA, HNRNPR, EIF4A3, ILF2, HNRNPU, DHX15, DHX9, KCND3, PPP1CC, PPP1CB, PPP1CA, TCF3, ARRB2, SUMO2, HIST2H4A, HIST1H3A, tat, CBX5, SRPK1, FNBP4, AKAP8L, YWHAG, CBX3, LBR, PRM1, LMNB1, MECP2,
Protein Size: 615

Poids moléculaire: 71 kDa

ID gène: 3930

NCBI Accession: NM_002296, NP_002287

UniProt: Q14739