PI3 anticorps (Middle Region)

N° du produit ABIN2782187

Cet anticorps anti-PI3 Polyclonal Lapin (ABIN2782187) détecte spécifiquement PI3 dans WB. L’anticorps est réactif avec des échantillons de Humain, Boeuf (Vache), Porc et Mouton.

Aperçu rapide pour PI3 anticorps (Middle Region) (ABIN2782187)

Antigène: PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

Reactivité: Humain, Boeuf (Vache), Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PI3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PI3 anticorps

Épitope: Middle Region

Fonction: PI3 Antibody - middle region

Séquence: KGRVPFNGQD PVKGQVSVKG QDKVKAQEPV KGPVSTKPGS CPIILIRCAM

Homologie: Cow: 85%, Human: 100%, Pig: 77%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against PI3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PI3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45341-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PI3

Antigène: PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

Autre désignation: PI3

Sujet:

Background Information: PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Peptidase inhibitor 3, skin-derived

Alternative Symbols: ESI, WAP3, SKALP, WFDC14, cementoin

Protein Name: Elafin

Poids moléculaire: 6kDa

ID gène: 5266

NCBI Accession: NP_002629

UniProt: P19957