PI3 anticorps (Middle Region)

N° du produit ABIN2782187

Détail du produit anti-PI3 anticorps

Antigène: PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

Épitope: Middle Region

Reactivité: Humain, Boeuf (Vache), Porc, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PI3 est non-conjugé

Application: Western Blotting (WB)

Séquence: KGRVPFNGQD PVKGQVSVKG QDKVKAQEPV KGPVSTKPGS CPIILIRCAM

Homologie: Cow: 85%, Human: 100%, Pig: 77%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against PI3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PI3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 117 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PI3

Antigène: PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

Autre désignation: PI3 (PI3 Produits)

Synonymes: anticorps ESI, anticorps SKALP, anticorps WAP3, anticorps WFDC14, anticorps cementoin, anticorps trappin-2, anticorps TRAPPIN-2, anticorps elafin, anticorps peptidase inhibitor 3, anticorps peptidase inhibitor 3, skin-derived (SKALP), anticorps PI3

Sujet: PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin
Protein Interaction Partner: EVPL, CELA1, LOR, KRT1, CSTA,
Protein Size: 117

Poids moléculaire: 6 kDa

ID gène: 5266

NCBI Accession: NM_002638, NP_002629

UniProt: P19957