Transferrin Receptor 2 anticorps (Middle Region)

N° du produit ABIN2782222

Détail du produit anti-Transferrin Receptor 2 anticorps

Antigène: Transferrin Receptor 2 (TFR2)

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transferrin Receptor 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: YVSLDNAVLG DDKFHAKTSP LLTSLIESVL KQVDSPNHSG QTLYEQVVFT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TFR2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TFR2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 801 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Transferrin Receptor 2

Antigène: Transferrin Receptor 2 (TFR2)

Autre désignation: TFR2 (TFR2 Produits)

Synonymes: anticorps TFR2, anticorps Trfr2, anticorps HFE3, anticorps TFRC2, anticorps zgc:123043, anticorps transferrin receptor 2, anticorps TFR2, anticorps Tfr2, anticorps tfr2

Sujet: TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HFE3, MGC126368, TFRC2
Protein Interaction Partner: FBXO6, ATP4A, SOCS3, UBC, HFE, TF,
Protein Size: 801

Poids moléculaire: 89 kDa

ID gène: 7036

NCBI Accession: NM_003227, NP_003218

UniProt: Q9UP52

Pathways: Transition Metal Ion Homeostasis