TGFB2 anticorps (Middle Region)

N° du produit ABIN2782223

L’anticorps Lapin Polyclonal anti-TGFB2 a été validé pour WB. Il convient pour détecter TGFB2 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cheval, Mouton, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour TGFB2 anticorps (Middle Region) (ABIN2782223)

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cheval, Mouton, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TGFB2 anticorps

Épitope: Middle Region

Séquence: NLVKAEFRVF RLQNPKARVP EQRIELYQIL KSKDLTSPTQ RYIDSKVVKT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TGFB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TGFB2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 414 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TGFB2

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Autre désignation: TGFB2

Sujet: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC116892, TGF-beta2
Protein Interaction Partner: CEBPA, UBC, VASN, PZP, LTBP3, TGFBR3, FMOD, VTN, TGFB3, TGFB2, TGFBR2, TGFBR1, TGFB1, ENG, CTGF, BMP2, APP, TGFBRAP1, DAXX, DCN,
Protein Size: 414

Poids moléculaire: 46 kDa

ID gène: 7042

NCBI Accession: NM_003238, NP_003229

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus