ZP2 anticorps (C-Term)

N° du produit ABIN2782230

Cet anticorps anti-ZP2 Polyclonal Lapin (ABIN2782230) détecte spécifiquement ZP2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Cheval, Cobaye, Lapin, Boeuf (Vache) et Chien.

Aperçu rapide pour ZP2 anticorps (C-Term) (ABIN2782230)

Antigène: ZP2 (Zona Pellucida Glycoprotein 2 (ZP2))

Reactivité: Humain, Rat, Cheval, Cobaye, Lapin, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZP2 anticorps

Épitope: C-Term

Fonction: ZP2 Antibody - C-terminal region

Séquence: PDSFPQWNVV VDGCAYDLDN YQTTFHPVGS SVTHPDHYQR FDMKAFAFVS

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ZP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ZP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8117258

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZP2

Antigène: ZP2 (Zona Pellucida Glycoprotein 2 (ZP2))

Autre désignation: ZP2

Sujet:

Background Information: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. ZP2 is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies.

Gene Name: Zona pellucida glycoprotein 2 (sperm receptor)

Alternative Symbols: ZPA, Zp-2, OOMD6

Protein Name: Zona pellucida sperm-binding protein 2

Poids moléculaire: 68kDa

ID gène: 7783

NCBI Accession: NP_003451

UniProt: Q05996