CNTNAP1 anticorps (N-Term)

N° du produit ABIN2782237

L’anticorps Lapin Polyclonal anti-CNTNAP1 a été validé pour WB. Il convient pour détecter CNTNAP1 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval et Lapin.

Aperçu rapide pour CNTNAP1 anticorps (N-Term) (ABIN2782237)

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTNAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CNTNAP1 anticorps

Épitope: N-Term

Séquence: LQIDLMKKHR IRAVATQGSF NSWDWVTRYM LLYGDRVDSW TPFYQRGHNS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CNTNAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CNTNAP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1384 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CNTNAP1

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Autre désignation: CNTNAP1

Sujet: CNTNAP1 was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,381-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.
Alias Symbols: CASPR, CNTNAP, NRXN4, P190
Protein Interaction Partner: UBC, vpu, FBXO6, NFASC, RTN4, SRC, PTPRB, RHOA, FYN, RAC1, CDC42, KCNA1, KCNA2,
Protein Size: 1384

Poids moléculaire: 156 kDa

ID gène: 8506

NCBI Accession: NM_003632, NP_003623

UniProt: P78357

Pathways: Cell-Cell Junction Organization