Retinoic Acid Receptor beta anticorps (C-Term)

N° du produit ABIN2782266

Détail du produit anti-Retinoic Acid Receptor beta anticorps

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoic Acid Receptor beta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SAKGAERVIT LKMEIPGSMP PLIQEMLENS EGHEPLTPSS SGNTAEHSPS

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RARB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RARB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 448 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Retinoic Acid Receptor beta

Antigène: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Autre désignation: RARB (RARB Produits)

Synonymes: anticorps RARB, anticorps nRARs, anticorps HAP, anticorps NR1B2, anticorps RRB2, anticorps A830025K23, anticorps Hap, anticorps Nr1b2, anticorps RARbeta2, anticorps RARBETA, anticorps retinoic acid receptor beta, anticorps retinoic acid receptor, beta, anticorps RARB, anticorps Rarb

Sujet: RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants, one additional transcript has been described, but its full length nature has not been determined.
Alias Symbols: HAP, NR1B2, RRB2
Protein Interaction Partner: RXRG, RXRB, MEOX2, ITGB1BP2, PRKD2, SMAD2, CCNH, HACE1, PNRC1, NCOR2, EIF3I, NCOA1, MAP6, SRC, RXRA, HR, GATA3, NCOA3, CEBPB, CEBPA, NR4A2, DNMT3B, DNMT3A, DNMT1, HIST4H4, HDAC1,
Protein Size: 448

Poids moléculaire: 50 kDa

ID gène: 5915

NCBI Accession: NM_000965, NP_000956

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway