ESRRA anticorps (N-Term)

N° du produit ABIN2782281

Détail du produit anti-ESRRA anticorps

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRRA est non-conjugé

Application: Western Blotting (WB)

Séquence: KEGVRLDRVR GGRQKYKRRP EVDPLPFPGP FPAGPLAVAG GPRKTAAPVN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ESRRA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ESRRA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 423 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ESRRA

Antigène: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Autre désignation: ESRRA (ESRRA Produits)

Synonymes: anticorps err1, anticorps erra, anticorps esrral, anticorps erralpha, anticorps nr3b1, anticorps MGC80854, anticorps ESRRA, anticorps esrl1, anticorps LOC100125507, anticorps ERRalpha, anticorps Err1, anticorps Estrra, anticorps Nr3b1, anticorps Errra, anticorps ERR1, anticorps ERRa, anticorps ESRL1, anticorps NR3B1, anticorps ESTRRA, anticorps estrogen-related receptor alpha, anticorps estrogen related receptor alpha L homeolog, anticorps estrogen related receptor alpha, anticorps catsper channel auxiliary subunit zeta, anticorps estrogen related receptor, alpha, anticorps esrra, anticorps esrra.L, anticorps ESRRA, anticorps LOC100125507, anticorps CATSPERZ, anticorps Esrra

Sujet: ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERR1, ERRa, ERRalpha, ESRL1, NR3B1
Protein Interaction Partner: SUMO2, SUMO3, NSD1, NCOA1, EXOSC6, SMARCD3, ESR1, PIAS4, NXF1, ATXN1, MAP2K5, FUS, ADH5, WDR36, ZNF606, C2CD5, IPO13, TFAP4, Cebpb, ESRRG, PPARGC1A, MACF1, EIF3I, NR0B2, NRIP1, NCOA3, TNNI2, SRC, PROX1, DUT, NR0B1, UBC, PARK2, ZNF658B, SPICE1, KDM3B, DPF1
Protein Size: 423

Poids moléculaire: 46 kDa

ID gène: 2101

NCBI Accession: NM_004451, NP_004442

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha