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Retinoid X Receptor gamma anticorps (N-Term)

RXRG Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Cobaye, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782291
  • Antigène Voir toutes Retinoid X Receptor gamma (RXRG) Anticorps
    Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
    Épitope
    • 15
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 59
    • 21
    • 18
    • 10
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval, Cobaye, Lapin
    Hôte
    • 47
    • 11
    • 1
    Lapin
    Clonalité
    • 49
    • 10
    Polyclonal
    Conjugué
    • 34
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Retinoid X Receptor gamma est non-conjugé
    Application
    • 29
    • 22
    • 13
    • 13
    • 9
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    NVVNSVSSSE DIKPLPGLPG IGNMNYPSTS PGSLVKHICA ICGDRSSGKH
    Homologie
    Cow: 100%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against RXRG. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human RXRG
    Top Product
    Discover our top product RXRG Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 463 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bungard, McGivan: "Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers." dans: Archives of biochemistry and biophysics, Vol. 443, Issue 1-2, pp. 53-9, (2005) (PubMed).

  • Antigène
    Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
    Autre désignation
    RXRG (RXRG Produits)
    Synonymes
    anticorps NR2B3, anticorps RXRC, anticorps zgc:92183, anticorps RXRgamma, anticorps RXRG, anticorps RXR-gamma, anticorps nr2b3, anticorps xrxrg, anticorps rxrc, anticorps Nr2b3, anticorps NR2B1, anticorps RXR, anticorps rxra, anticorps rxrg, anticorps retinoid X receptor gamma, anticorps retinoid X receptor, gamma b, anticorps retinoid X receptor gamma L homeolog, anticorps retinoid x receptor, gamma a, anticorps RXRG, anticorps rxrgb, anticorps rxrg.L, anticorps rxrg, anticorps Rxrg, anticorps RXRGAMMA, anticorps rxrga
    Sujet
    RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: NR2B3, RXRC
    Protein Interaction Partner: NR1H3, NR1H2, RARB, RARA, MPPED2, UBC, CUL1, DCK, NR1H4, NCOR2, NR1I2, VDR, THRB, RARG, PPARD, MAP4, CAMK2B, CEBPZ, HOXD4, AJUBA, RPAP2, LRSAM1, PNO1, CHGB, THRA, NCOA6, PPARG, SRF, CREBBP, PPARA, NR4A1, Nr0b2, ITGB3BP,
    Protein Size: 463
    Poids moléculaire
    51 kDa
    ID gène
    6258
    NCBI Accession
    NM_006917, NP_008848
    UniProt
    P48443
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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