Liver Arginase anticorps (N-Term)

N° du produit ABIN502663

Cet anticorps Lapin Polyclonal détecte spécifiquement Liver Arginase dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Chien, Porc, Cheval, Chévre et Saccharomyces cerevisiae.Il a été cité dans 1 publication.

Aperçu rapide pour Liver Arginase anticorps (N-Term) (ABIN502663)

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Chien, Porc, Cheval, Chévre, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Liver Arginase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Liver Arginase anticorps

Épitope: N-Term

Fonction: ARG1 Antibody - N-terminal region

Séquence: SAKSRTIGII GAPFSKGQPR GGVEEGPTVL RKAGLLEKLK EQECDVKDYG

Réactivité croisée: Boeuf (Vache), Humain, Souris, Porc, Lapin, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ARG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ARG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45671-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Liver Arginase (ABIN502663)

Kitowska, Zakrzewicz, Königshoff, Chrobak, Grimminger, Seeger, Bulau, Eickelberg: "Functional role and species-specific contribution of arginases in pulmonary fibrosis." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 1, pp. L34-45, (2008) (PubMed).

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: ARG1

Sujet:

Background Information: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Arginase, liver

Alternative Symbols: -

Protein Name: Arginase-1

Poids moléculaire: 35kDa

ID gène: 383

NCBI Accession: NP_000036

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin