KNG1 anticorps (Middle Region)

N° du produit ABIN2782314

Il existe 1 publication pour ce produit. L’anticorps anti-KNG1 Polyclonal Lapin est utilisé pour la détection de KNG1 dans des échantillons de Humain, Souris, Porc et Cheval. Il a été validé pour WB.

Aperçu rapide pour KNG1 anticorps (Middle Region) (ABIN2782314)

Antigène: KNG1 (Kininogen 1 (KNG1))

Reactivité: Humain, Souris, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNG1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KNG1 anticorps

Épitope: Middle Region

Fonction: KNG1 Antibody - middle region

Séquence: YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK

Homologie: Horse: 85%, Human: 100%, Mouse: 77%, Pig: 92%

Attributs du produit: This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KNG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45680-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-KNG1 (ABIN2782314)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Détails sur KNG1

Antigène: KNG1 (Kininogen 1 (KNG1))

Autre désignation: KNG1

Sujet:

Background Information: Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.

Gene Name: Kininogen 1

Alternative Symbols: BK, BDK, KNG, HMWK

Protein Name: Kininogen-1

Poids moléculaire: 72kDa

ID gène: 3827

NCBI Accession: NP_001095886

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process