KNG1 anticorps (Middle Region)

N° du produit ABIN2782314

Détail du produit anti-KNG1 anticorps

Antigène: KNG1 (Kininogen 1 (KNG1))

Épitope: Middle Region

Reactivité: Humain, Souris, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNG1 est non-conjugé

Application: Western Blotting (WB)

Séquence: YPGKDFVQPP TKICVGCPRD IPTNSPELEE TLTHTITKLN AENNATFYFK

Homologie: Horse: 85%, Human: 100%, Mouse: 77%, Pig: 92%

Attributs du produit: This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KNG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 644 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-KNG1 (ABIN2782314)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Détails sur KNG1

Antigène: KNG1 (Kininogen 1 (KNG1))

Autre désignation: KNG1 (KNG1 Produits)

Synonymes: anticorps BDK, anticorps BK, anticorps KNG, anticorps Kng, anticorps KNG2, anticorps fb64g01, anticorps wu:fb64g01, anticorps zgc:103569, anticorps kininogen, anticorps bdk, anticorps kng, anticorps KNG1, anticorps IHRP, anticorps KINKG, anticorps KINKH, anticorps Kng1, anticorps Kngk, anticorps kininogen 1, anticorps kininogen 1 L homeolog, anticorps inter-alpha-trypsin inhibitor heavy chain family member 4, anticorps kininogen 2-like 1, anticorps KNG1, anticorps Kng1, anticorps kng1, anticorps kng1.L, anticorps ITIH4, anticorps Kng2l1

Sujet: Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.
Alias Symbols: BDK, KNG
Protein Interaction Partner: Ance, ECE1, COPS6, RXFP4, CPN1, F11, HABP2, CTSK, PREP, MEP1A, ITGB2, GP1BA, KLKB1, KNG1, VTN, THBS1, F2, PLAUR, PLG, KLK1, KRT1, FTL, ELANE, CD93, CTSL, CTSS, CTSG, CAPN2, CAPN1, AGT, APP,
Protein Size: 644

Poids moléculaire: 72 kDa

ID gène: 3827

NCBI Accession: NM_001102416, NP_001095886

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process