KNG1 anticorps (C-Term)
Aperçu rapide pour KNG1 anticorps (C-Term) (ABIN2782315)
Antigène
Voir toutes KNG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- ISLMKRPPGF SPFRSSRIGE IKEETTSHLR SCEYKGRPPK AGAEPASERE
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Homologie
- Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of human KNG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KNG1 (Kininogen 1 (KNG1))
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Autre désignation
- KNG1
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Sujet
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This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BK, BDK, KNG
Protein Size: 291 -
Poids moléculaire
- 32 kDa
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ID gène
- 3827
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NCBI Accession
- NM_000893, NP_000884
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Pathways
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
Antigène
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