KNG1 anticorps (C-Term)

N° du produit ABIN2782315

Cet anticorps anti-KNG1 Polyclonal Lapin (ABIN2782315) détecte spécifiquement KNG1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour KNG1 anticorps (C-Term) (ABIN2782315)

Antigène: KNG1 (Kininogen 1 (KNG1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNG1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KNG1 anticorps

Épitope: C-Term

Fonction: KNG1 Antibody - C-terminal region

Séquence: ISLMKRPPGF SPFRSSRIGE IKEETTSHLR SCEYKGRPPK AGAEPASERE

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KNG1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human KNG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45681-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur KNG1

Antigène: KNG1 (Kininogen 1 (KNG1))

Autre désignation: KNG1

Sujet:

Background Information: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: kininogen 1

Alternative Symbols: BK, BDK, KNG, HMWK

Protein Name: kininogen-1

Poids moléculaire: 32kDa

ID gène: 3827

NCBI Accession: NP_000884

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process