HAL anticorps (C-Term)

N° du produit ABIN2782321

Détail du produit anti-HAL anticorps

Antigène: HAL (Histidine Ammonia-Lyase (HAL))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: EAAHRLLLEQ KVWEVAAPYI EKYRMEHIPE SRPLSPTAFS LQFLHKKSTK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against HAL. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HAL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 657 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HAL (ABIN2782321)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Alemán, Ortíz, Langley, Tovar, Torres: "Regulation by glucagon of the rat histidase gene promoter in cultured rat hepatocytes and human hepatoblastoma cells." dans: American journal of physiology. Endocrinology and metabolism, Vol. 289, Issue 1, pp. E172-9, (2005) (PubMed).

Détails sur HAL

Antigène: HAL (Histidine Ammonia-Lyase (HAL))

Autre désignation: HAL (HAL Produits)

Synonymes: anticorps HIS, anticorps HSTD, anticorps hal, anticorps hstd, anticorps xhal, anticorps HAL, anticorps BA3712, anticorps DDBDRAFT_0187742, anticorps DDBDRAFT_0231727, anticorps DDB_0187742, anticorps DDB_0231727, anticorps zgc:136980, anticorps his, anticorps Hsd, anticorps histidase, anticorps histidine ammonia-lyase, anticorps histidine ammonia-lyase, gene 1 L homeolog, anticorps histidine ammonia-lyase HutH, anticorps histidine ammonia-lyase, gene 1, anticorps histidine ammonia lyase, anticorps HAL, anticorps hal.1.L, anticorps hutH, anticorps Tc00.1047053506247.220, anticorps Plav_1493, anticorps hal, anticorps hal.1, anticorps Hal

Sujet: HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluidsHistidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.
Alias Symbols: HIS, HSTD
Protein Interaction Partner: UBC,
Protein Size: 657

Poids moléculaire: 72 kDa

ID gène: 3034

NCBI Accession: NM_002108, NP_002099

UniProt: P42357