CSTB anticorps (Middle Region)
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- Antigène Voir toutes CSTB Anticorps
- CSTB (Cystatin B (Stefin B) (CSTB))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Cheval, Porc, Chien, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CSTB est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- AGTNYFIKVH VGDEDFVHLR VFQSLPHENK PLTLSNYQTN KAKHDELTYF
- Homologie
- Dog: 92%, Horse: 85%, Human: 100%, Mouse: 83%, Pig: 79%, Rabbit: 77%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against CSTB. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CSTB
- Top Product
- Discover our top product CSTB Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 98 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CSTB (Cystatin B (Stefin B) (CSTB))
- Autre désignation
- CSTB (CSTB Produits)
- Synonymes
- anticorps CST6, anticorps EPM1, anticorps EPM1A, anticorps PME, anticorps STFB, anticorps ULD, anticorps CSTB, anticorps Cyb, anticorps Epm1, anticorps Stfb, anticorps MGC189005, anticorps pme, anticorps cst6, anticorps epm1, anticorps stfb, anticorps AA960480, anticorps ARABIDOPSIS THALIANA PHYTOCYSTATIN 6, anticorps ATCYS6, anticorps ATCYSB, anticorps cystatin B, anticorps LOC100008600, anticorps LOC100136235, anticorps CPI1, anticorps cystatin B, anticorps cystatin B (stefin B), anticorps cystatin 14a, tandem duplicate 2, anticorps cystatin-B, anticorps CSTB, anticorps Cstb, anticorps cstb, anticorps cst14a.2, anticorps CYSB, anticorps cpi1, anticorps LOC101123265
- Sujet
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CSTB is a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in CSTB gene are responsible for the primary defects in patients with progressive myoclonic epilepsy a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy.The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Alias Symbols: CST6, EPM1, PME, STFB, ULD, EPM1A
Protein Interaction Partner: UBC, SARNP, DPP7, BAG3, CFTR, ECT2, SEC24A, NUDC, MAT2A, FLNB, DCUN1D1, CUL3, RAD21, SPRY2, CTSL, CTSD, CTSH, CTSB, CST3, VHL,
Protein Size: 98 - Poids moléculaire
- 11 kDa
- ID gène
- 1476
- NCBI Accession
- NM_000100, NP_000091
- UniProt
- P04080
- Pathways
- Response to Water Deprivation
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