SOD1 anticorps (N-Term)

N° du produit ABIN2782351

Détail du produit anti-SOD1 anticorps

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MATKAVCVLK GDGPVQGIIN FEQKESNGPV KVWGSIKGLT EGLHGFHVHE

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SOD1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SOD1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 154 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SOD1 (ABIN2782351)

Hays, Naini, He, Mitsumoto, Rowland: "Sporadic amyotrophic lateral sclerosis and breast cancer: Hyaline conglomerate inclusions lead to identification of SOD1 mutation." dans: Journal of the neurological sciences, Vol. 242, Issue 1-2, pp. 67-9, (2006) (PubMed).

Détails sur SOD1

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Autre désignation: SOD1 (SOD1 Produits)

Synonymes: anticorps LOC692639, anticorps ALS, anticorps ALS1, anticorps IPOA, anticorps SOD, anticorps hSod1, anticorps homodimer, anticorps CG11793, anticorps Cu, anticorps Cu-Zn SOD, anticorps Cu/Zn SOD, anticorps Cu/Zn sod, anticorps Cu/Zn superoxide dismutase, anticorps Cu/ZnSOD, anticorps CuSOD, anticorps CuZn SOD, anticorps CuZn-SOD, anticorps CuZn-SOD1, anticorps CuZnSOD, anticorps Cu[2+]/Zn[2+]SOD, anticorps Dmel\\CG11793, anticorps G, anticorps Mn SOD, anticorps SOD-1, anticorps SOD1, anticorps Sod-1, anticorps Sod1, anticorps To, anticorps To-1, anticorps Zn SOD, anticorps Zn Sod, anticorps Zn-SOD, anticorps ZnSod, anticorps cSOD, anticorps cSod, anticorps dSOD1, anticorps l(3)108, anticorps l(3)68Af', anticorps l(3)G, anticorps sod, anticorps sod1, anticorps CU/ZN-SOD, anticorps SODC, anticorps DKFZP469M1833, anticorps B430204E11Rik, anticorps Cu/Zn-SOD, anticorps Ipo-1, anticorps Ipo1, anticorps SOD1L1, anticorps XSODB, anticorps als, anticorps als1, anticorps ipoa, anticorps sod1-a, anticorps ZSOD, anticorps cuzn, anticorps Cu/Zn superoxide dismutase, anticorps superoxide dismutase 1, anticorps Superoxide dismutase 1, anticorps superoxide dismutase 1, soluble, anticorps superoxide dismutase 1 S homeolog, anticorps Superoxide dismutase [Cu-Zn], anticorps superoxide dismutase 1 L homeolog, anticorps superoxide dismutase [Cu-Zn]-like, anticorps superoxide dismutase [Cu-Zn], anticorps superoxide dismutase Sod1, anticorps SOD, anticorps SOD1, anticorps Sod1, anticorps sod1, anticorps sod1.S, anticorps sod-1, anticorps sod1.L, anticorps LOC101451855, anticorps LOC101115136

Sujet: SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Alias Symbols: ALS, ALS1, IPOA, SOD, homodimer, hSod1
Protein Interaction Partner: SOD1, CRYAB, UBC, SMAD2, HDAC6, GSH1, OPTN, PRDX5, AHCYL1, TIAL1, PRDX2, SPTBN1, SOD2, PPP2CA, PPIA, PLS3, PRDX1, NME2, NME1, Hspa4l, Hspa4, Hspa2, Hspa1b, Hsph1, Dnaja1, Hspa8, Hspa5, Ccs, UBE3A, COMMD1, Stub1, SUMO4, DYNLT1, AMFR, MARCH5, RNF19A, PSMD4,
Protein Size: 154

Poids moléculaire: 16 kDa

ID gène: 6647

NCBI Accession: NM_000454, NP_000445

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis