CHAF1B anticorps (N-Term)

N° du produit ABIN2782376

Détail du produit anti-CHAF1B anticorps

Antigène: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Porc, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHAF1B est non-conjugé

Application: Western Blotting (WB)

Séquence: KVITCEIAWH NKEPVYSLDF QHGTAGRIHR LASAGVDTNV RIWKVEKGPD

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CHAF1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CHAF1B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 559 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CHAF1B (ABIN2782376)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." dans: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Détails sur CHAF1B

Antigène: CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))

Autre désignation: CHAF1B (CHAF1B Produits)

Synonymes: anticorps CHAF1B, anticorps wu:fd07c09, anticorps wu:fe36g06, anticorps wu:fv38g09, anticorps zgc:56096, anticorps CAF-1, anticorps CAF-IP60, anticorps CAF1, anticorps CAF1A, anticorps CAF1P60, anticorps MPHOSPH7, anticorps MPP7, anticorps 2600017H24Rik, anticorps C76145, anticorps CAF-I p60, anticorps CAF-Ip60, anticorps caf-1, anticorps CAF-1P60, anticorps chromatin assembly factor 1 subunit B, anticorps chromatin assembly factor 1, subunit B, anticorps chromatin assembly factor 1, subunit B (p60), anticorps chromatin assembly factor 1 subunit B L homeolog, anticorps CHAF1B, anticorps chaf1b, anticorps Chaf1b, anticorps chaf1b.L

Sujet: Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. CHAF1B corresponds to the p60 subunit and is required for chromatin assembly after replication. CHAF1B is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7
Protein Interaction Partner: UBC, SOX2, CNOT6L, env, CBX6, CBX5, HIST1H3B, HIST1H3A, CHAF1A, PCNA, APP, HIST2H3C, HIST1H4F, HIST1H3E, HIST3H3, SUMO2, BANF1, ASF1B, ASF1A, SETDB1, RBBP4, CDK2, CDK1,
Protein Size: 559

Poids moléculaire: 61 kDa

ID gène: 8208

NCBI Accession: NM_005441, NP_005432

UniProt: Q13112