GM2A anticorps (N-Term)

N° du produit ABIN2782426

Cet anticorps Lapin Polyclonal détecte spécifiquement GM2A dans WB. Il présente une réactivité envers Humain et Cobaye.

Aperçu rapide pour GM2A anticorps (N-Term) (ABIN2782426)

Antigène: GM2A (GM2 Ganglioside Activator (GM2A))

Reactivité: Humain, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GM2A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GM2A anticorps

Épitope: N-Term

Séquence: SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL

Homologie: Guinea Pig: 83%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GM2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GM2A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 193 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GM2A

Antigène: GM2A (GM2 Ganglioside Activator (GM2A))

Autre désignation: GM2A

Sujet: This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: SAP-3, GM2-AP
Protein Interaction Partner: ELAVL1, UBC, HEXA, GPLD1, PLD2,
Protein Size: 193

Poids moléculaire: 21 kDa

ID gène: 2760

NCBI Accession: NM_000405, NP_000396

UniProt: P17900