GUCY1B3 anticorps (N-Term)
Aperçu rapide pour GUCY1B3 anticorps (N-Term) (ABIN2782430)
Antigène
Voir toutes GUCY1B3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- GUCY1B1 Antibody - N-terminal region
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Séquence
- LIEEKESKEE DFYEDLDRFE ENGTQESRIS PYTFCKAFPF HIIFDRDLVV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against GUCY1B3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human GUCY1B3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46012-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))
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Autre désignation
- GUCY1B1
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Sujet
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Targeted Subunit: beta-1
Background Information: This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
Gene Name: guanylate cyclase 1 soluble subunit beta 1
Alternative Symbols: GUCB3, GC-SB3, GUC1B3, GUCSB3, GUCY1B3, GC-S-beta-1
Protein Name: guanylate cyclase soluble subunit beta-1
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Poids moléculaire
- 70kDa
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ID gène
- 2983
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NCBI Accession
- NP_000848
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UniProt
- Q02153
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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