MTHFD2 anticorps (N-Term)

N° du produit ABIN2782446

Cet anticorps Lapin Polyclonal détecte spécifiquement MTHFD2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Lapin, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio) et Saccharomyces cerevisiae et a été mentionné dans 1 publication.

Aperçu rapide pour MTHFD2 anticorps (N-Term) (ABIN2782446)

Antigène: MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin, Cheval, Boeuf (Vache), Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTHFD2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MTHFD2 anticorps

Épitope: N-Term

Séquence: LPLPEHIDER RICNAVSPDK DVDGFHVINV GRMCLDQYSM LPATPWGVWE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MTHFD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MTHFD2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 350 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MTHFD2 (ABIN2782446)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur MTHFD2

Antigène: MTHFD2 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase (MTHFD2))

Autre désignation: MTHFD2

Sujet: MTHFD2 is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in multiple transcripts encoding different isoforms. This gene has a pseudogene on chromosome 7.
Alias Symbols: NMDMC
Protein Interaction Partner: NAGK, HUWE1, UBC, MDM2, nef, DHX40, GCC1, DHX29, CUL3, ELAVL1, MINOS1, PARP3, PSMD13,
Protein Size: 350

Poids moléculaire: 35 kDa

ID gène: 10797

NCBI Accession: NM_006636, NP_006627

UniProt: P13995