PAICS anticorps (N-Term)

N° du produit ABIN2782454

Détail du produit anti-PAICS anticorps

Antigène: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAICS est non-conjugé

Application: Western Blotting (WB)

Séquence: ATAEVLNIGK KLYEGKTKEV YELLDSPGKV LLQSKDQITA GNAARKNHLE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PAICS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PAICS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 425 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAICS

Antigène: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Autre désignation: PAICS (PAICS Produits)

Synonymes: anticorps cb293, anticorps sb:cb293, anticorps wu:fa28a05, anticorps GB14262, anticorps DDBDRAFT_0218550, anticorps DDBDRAFT_0230088, anticorps DDB_0218550, anticorps DDB_0230088, anticorps AIRC, anticorps AS, anticorps ADE2, anticorps ADE2H1, anticorps PAIS, anticorps Ade2h1, anticorps Airc, anticorps ade2, anticorps airc, anticorps paics, anticorps pais, anticorps 2610511I09Rik, anticorps phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase, anticorps phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, anticorps multifunctional protein ADE2, anticorps phosphoribosylaminoimidazole carboxylase, anticorps phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog, anticorps phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase, anticorps PAICS, anticorps paics, anticorps LOC551966, anticorps Tsp_02239a, anticorps Tsp_02239, anticorps CNE02500, anticorps purC/E, anticorps Paics, anticorps paics.2.L

Sujet: PAICS is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADE2, ADE2H1, AIRC, DKFZp781N1372, MGC1343, MGC5024, PAIS
Protein Interaction Partner: L3MBTL2, PAICS, HUWE1, UBC, FUS, WWOX, QRICH1, SWAP70, FARSB, SUPT5H, SET, PRKCSH, FXR2, NUDT18, SMARCD1, PRKAG1, FN1, NIF3L1, TP53BP1, UNK, GINS4, TMEM177, RPAP1, SSSCA1, TACC3, STUB1, PUM1, ZPR1, UBE2B, TTC1, NDUFV1, GART, UBD, CUL3, CDK2, TERF1, SIRT7,
Protein Size: 425

Poids moléculaire: 47 kDa

ID gène: 10606

NCBI Accession: NM_001079524, NP_001072992

UniProt: P22234

Pathways: Chromatin Binding