HIST1H1C anticorps (Middle Region)
Aperçu rapide pour HIST1H1C anticorps (Middle Region) (ABIN2782497)
Antigène
Voir toutes HIST1H1C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS
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Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against HIST1H1C. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1C
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 213 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))
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Autre désignation
- HIST1H1C
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Sujet
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Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H1.2, H1F2, MGC3992, H1C
Protein Interaction Partner: UBC, CEP250, ATRX, HIST1H3A, LEO1, PAF1, CUL4A, POLR2A, MDM2, ASB16, ASB9, SUZ12, EED, RNF2, APEH, SEC24D, TBCD, PARK2, VHL, UBD, ICAM1, CD81, IGSF8, EIF2AK2, ITGA4, IL7R, CSNK2A2, SMURF1, HIST1H2AD, H1FX, COPS5, CAND1, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD
Protein Size: 213 -
Poids moléculaire
- 21 kDa
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ID gène
- 3006
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NCBI Accession
- NM_005319, NP_005310
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UniProt
- P16403
Antigène
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