SMC2 anticorps (Middle Region)

N° du produit ABIN2782520

L’anticorps Lapin Polyclonal anti-SMC2 a été validé pour WB. Il convient pour détecter SMC2 dans des échantillons de Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Lapin, Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour SMC2 anticorps (Middle Region) (ABIN2782520)

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reactivité: Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SMC2 anticorps

Épitope: Middle Region

Séquence: ATLAGQMMAC KNDISKAQTE AKQAQMKLKH AQQELKNKQA EVKKMDSGYR

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SMC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1197 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMC2

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Autre désignation: SMC2

Sujet: SMC2 belongs to the SMC family. It is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAP-E, CAPE, FLJ10093, SMC2L1, hCAP-E
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, NCAPG, CCAR2, NCAPH, SSSCA1, SMC4, NCAPD2, PLEC, CDK9, FBXO6, EGFR, SOX2, GULP1, ABCC5, PAXIP1, SMC1A, UBD, NEDD8, SUMO2, NCAPG2, NCAPH2, NCAPD3, RAD21, LIG4, HIST2H3C, DISC1, TRAF3IP1, HIST2H2BE, HIST2H2AC, H2AFZ, MYC, tat, DNMT3B,
Protein Size: 1197

Poids moléculaire: 136 kDa

ID gène: 10592

NCBI Accession: NM_006444, NP_006435

UniProt: O95347