SMC2 anticorps (Middle Region)
Aperçu rapide pour SMC2 anticorps (Middle Region) (ABIN2782520)
Antigène
Voir toutes SMC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- SMC2 Antibody - middle region
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Séquence
- ATLAGQMMAC KNDISKAQTE AKQAQMKLKH AQQELKNKQA EVKKMDSGYR
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against SMC2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SMC2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46156-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))
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Autre désignation
- SMC2
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Sujet
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Background Information: SMC2 belongs to the SMC family. It is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Gene Name: Structural maintenance of chromosomes 2
Alternative Symbols: CAPE, CAP-E, SMC-2, SMC2L1
Protein Name: Structural maintenance of chromosomes protein 2
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Poids moléculaire
- 136kDa
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ID gène
- 10592
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NCBI Accession
- NP_006435
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UniProt
- O95347
Antigène
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