SMC2 anticorps (Middle Region)

N° du produit ABIN2782520

Détail du produit anti-SMC2 anticorps

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC2 est non-conjugé

Application: Western Blotting (WB)

Séquence: ATLAGQMMAC KNDISKAQTE AKQAQMKLKH AQQELKNKQA EVKKMDSGYR

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SMC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SMC2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1197 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SMC2

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Autre désignation: SMC2 (SMC2 Produits)

Synonymes: anticorps CAP-E, anticorps CAPE, anticorps SMC-2, anticorps SMC2L1, anticorps 5730502P04Rik, anticorps AI255214, anticorps AW545314, anticorps Fin16, anticorps Smc2l1, anticorps fb92e05, anticorps wu:fb92e05, anticorps zeh1628, anticorps zgc:55326, anticorps xcap-e, anticorps SCII, anticorps structural maintenance of chromosomes 2, anticorps structural maintenance of chromosomes 2 L homeolog, anticorps SMC2, anticorps Smc2, anticorps smc2, anticorps smc2.L

Sujet: SMC2 belongs to the SMC family. It is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAP-E, CAPE, FLJ10093, SMC2L1, hCAP-E
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, NCAPG, CCAR2, NCAPH, SSSCA1, SMC4, NCAPD2, PLEC, CDK9, FBXO6, EGFR, SOX2, GULP1, ABCC5, PAXIP1, SMC1A, UBD, NEDD8, SUMO2, NCAPG2, NCAPH2, NCAPD3, RAD21, LIG4, HIST2H3C, DISC1, TRAF3IP1, HIST2H2BE, HIST2H2AC, H2AFZ, MYC, tat, DNMT3B,
Protein Size: 1197

Poids moléculaire: 136 kDa

ID gène: 10592

NCBI Accession: NM_006444, NP_006435

UniProt: O95347