PFAS anticorps (N-Term)

N° du produit ABIN2782529

Cet anticorps Lapin Polyclonal détecte spécifiquement PFAS dans WB. Il présente une réactivité envers Humain, Souris, Boeuf (Vache), Cobaye, Cheval et Lapin et a été mentionné dans 2+ publications.

Aperçu rapide pour PFAS anticorps (N-Term) (ABIN2782529)

Antigène: PFAS (Phosphoribosylformylglycinamidine Synthase (PFAS))

Reactivité: Humain, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFAS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PFAS anticorps

Épitope: N-Term

Séquence: ESIMSTQESS NPNNVLKFCD NSSAIQGKEV RFLRPEDPTR PSRFQQQQGL

Homologie: Cow: 83%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PFAS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PFAS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1338 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PFAS (ABIN2782529)

French, Zhao, An, Niessen, Deng, Cravatt, Benkovic: "Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 7, pp. 2528-33, (2013) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur PFAS

Antigène: PFAS (Phosphoribosylformylglycinamidine Synthase (PFAS))

Autre désignation: PFAS

Sujet: Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. PFAS catalyzes the fourth step of IMP biosynthesis. Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis.
Alias Symbols: FGAMS, FGARAT, KIAA0361, PURL
Protein Interaction Partner: UBC, SUMO2, TNRC6B, GINS3, ISOC1, BZW2, DCPS, MAT2B, ABHD14A, ERP44, PDCD10, FERMT2, NPEPPS, CNBP, YWHAZ, VCL, RAP1GDS1, PAK2, MSN, LDHB, HSPA9, EIF5, EEF2, ECHS1, DFFA, CKB, CAPN1, SGTA, XIAP, UBR1, USP28, PPP6R3, ZNF593, SEPHS1, CHERP, PRDX6, USP14, UBD
Protein Size: 1338

Poids moléculaire: 145 kDa

ID gène: 5198

NCBI Accession: NM_012393, NP_036525

UniProt: O15067