PDSS1 anticorps (Middle Region)

N° du produit ABIN2782535

Cet anticorps anti-PDSS1 Polyclonal Lapin (ABIN2782535) détecte spécifiquement PDSS1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Boeuf (Vache), Chien, Cobaye, Lapin, Rat et Cheval.

Aperçu rapide pour PDSS1 anticorps (Middle Region) (ABIN2782535)

Antigène: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cobaye, Lapin, Rat, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDSS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDSS1 anticorps

Épitope: Middle Region

Fonction: PDSS1 Antibody - middle region

Séquence: VIDDASSRRG KHTVNKIWGE KKAVLAGDLI LSAASIALAR IGNTTVISIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PDSS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PDSS1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46196-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDSS1

Antigène: PDSS1 (Prenyl (Decaprenyl) Diphosphate Synthase, Subunit 1 (PDSS1))

Autre désignation: PDSS1

Sujet:

Targeted Subunit: 1

Background Information: PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.

Gene Name: Prenyl (decaprenyl) diphosphate synthase, subunit 1

Alternative Symbols: DPS, SPS, TPT, COQ1, TPRT, COQ1A, TPT 1, hDPS1, COQ10D2

Protein Name: Decaprenyl-diphosphate synthase subunit 1

Poids moléculaire: 46kDa

ID gène: 23590

NCBI Accession: NP_055132

UniProt: Q5T2R2