SWAP70 anticorps (N-Term)
Aperçu rapide pour SWAP70 anticorps (N-Term) (ABIN2782542)
Antigène
Voir toutes SWAP70 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- ALEEHFRDDD EGPVSNQGYM PYLNRFILEK VQDNFDKIEF NRMCWTLCVK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against SWAP70. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human SWAP70
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 585 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Emissions from cooking microwave popcorn." dans: Critical reviews in food science and nutrition, Vol. 47, Issue 8, pp. 701-9, (2007) (PubMed).
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: "Emissions from cooking microwave popcorn." dans: Critical reviews in food science and nutrition, Vol. 47, Issue 8, pp. 701-9, (2007) (PubMed).
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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Autre désignation
- SWAP70
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Sujet
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Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Alias Symbols: FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Interaction Partner: ZBTB5, RAPGEF4, UBC, CORO1B, ASUN, OTUD6B, JMJD6, GANAB, PACSIN2, FAF1, PAICS, FARSB, ZRANB2, RANBP3, CUL1, SUPT5H, SET, PPP2R5C, PLOD2, OSBP, GART, XRCC6, CRMP1, ATP6V1B2, C18orf8, CELSR3, IGHG1, PARP1, NPM1, NCL,
Protein Size: 585 -
Poids moléculaire
- 69 kDa
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ID gène
- 23075
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NCBI Accession
- NM_015055, NP_055870
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UniProt
- Q9UH65
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Pathways
- Production of Molecular Mediator of Immune Response
Antigène
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