HRK anticorps (N-Term)

N° du produit ABIN2782598

Il existe 1 publication pour ce produit. L’anticorps anti-HRK Polyclonal Lapin est utilisé pour la détection de HRK dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Lapin. Il a été validé pour WB.

Aperçu rapide pour HRK anticorps (N-Term) (ABIN2782598)

Antigène: HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HRK anticorps

Épitope: N-Term

Fonction: HRK Antibody - N-terminal region

Séquence: MCPCPLHRGR GPPAVCACSA GRLGLRSSAA QLTAARLKAL GDELHQRTMW

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against HRK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HRK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46364-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HRK (ABIN2782598)

Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." dans: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

Détails sur HRK

Antigène: HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Autre désignation: HRK

Sujet:

Background Information: Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom

Gene Name: Harakiri, BCL2 interacting protein (contains only BH3 domain)

Alternative Symbols: DP5, HARAKIRI

Protein Name: Activator of apoptosis harakiri

Poids moléculaire: 10kDa

ID gène: 8739

NCBI Accession: NP_003797

UniProt: O00198