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HRK anticorps (N-Term)

HRK Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782598
  • Antigène Voir toutes HRK Anticorps
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Épitope
    • 15
    • 13
    • 7
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    • 28
    • 22
    • 17
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien
    Hôte
    • 43
    Lapin
    Clonalité
    • 43
    Polyclonal
    Conjugué
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HRK est non-conjugé
    Application
    • 18
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MCPCPLHRGR GPPAVCACSA GRLGLRSSAA QLTAARLKAL GDELHQRTMW
    Homologie
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 83%
    Attributs du produit
    This is a rabbit polyclonal antibody against HRK. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human HRK
    Top Product
    Discover our top product HRK Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 91 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." dans: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

  • Antigène
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Autre désignation
    HRK (HRK Produits)
    Synonymes
    anticorps DP5, anticorps HARAKIRI, anticorps AI838259, anticorps Bid3, anticorps harakiri, anticorps Dp5, anticorps harakiri, BCL2 interacting protein, anticorps harakiri, BCL2 interacting protein (contains only BH3 domain), anticorps HRK, anticorps Hrk
    Sujet
    Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom
    Alias Symbols: DP5, HARAKIRI
    Protein Interaction Partner: BCL2L1, ELAVL1, BAD, BCL2L2, C1QBP, BCL2A1, BCL2, MCL1, BNC1,
    Protein Size: 91
    Poids moléculaire
    10 kDa
    ID gène
    8739
    NCBI Accession
    NM_003806, NP_003797
    UniProt
    O00198
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