Cadherin 12 anticorps (Middle Region)

N° du produit ABIN2782614

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin 12 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Chien, Cobaye, Lapin, Boeuf (Vache), Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour Cadherin 12 anticorps (Middle Region) (ABIN2782614)

Antigène: Cadherin 12

Reactivité: Humain, Rat, Souris, Chien, Cobaye, Lapin, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cadherin 12 anticorps

Épitope: Middle Region

Séquence: DTQEGVIKLK KPLDFETKKA YTFKVEASNL HLDHRFHSAG PFKDTATVKI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CDH12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CDH12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 794 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cadherin 12

Antigène: Cadherin 12

Autre désignation: CDH12

Sujet: CDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Alias Symbols: CDHB, FLJ34857
Protein Interaction Partner: CDH7, CDH18,
Protein Size: 794

Poids moléculaire: 82 kDa

ID gène: 1010

NCBI Accession: NM_004061, NP_004052

UniProt: P55289