MMP20 anticorps (Middle Region)

N° du produit ABIN2782654

Détail du produit anti-MMP20 anticorps

Antigène: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP20 est non-conjugé

Application: Western Blotting (WB)

Séquence: AAVYLREPQK TLFFVGDEYY SYDERKRKME KDYPKNTEEE FSGVNGQIDA

Homologie: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MMP20. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MMP20

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 483 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MMP20

Antigène: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Autre désignation: MMP20 (MMP20 Produits)

Synonymes: anticorps AI2A2, anticorps MMP-20, anticorps MMP25, anticorps MMP20, anticorps mmp20, anticorps matrix metallopeptidase 20, anticorps matrix metallopeptidase 20 L homeolog, anticorps matrix metallopeptidase 20 (enamelysin), anticorps MMP20, anticorps mmp20.L, anticorps Mmp20

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP20 degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in the gene encoding MMP20, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta.
Alias Symbols: AI2A2, MMP-20
Protein Interaction Partner: ACAN,
Protein Size: 483

Poids moléculaire: 43 kDa

ID gène: 9313

NCBI Accession: NM_004771, NP_004762

UniProt: O60882