MMP20 anticorps (Middle Region)
Aperçu rapide pour MMP20 anticorps (Middle Region) (ABIN2782654)
Antigène
Voir toutes MMP20 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Fonction
- MMP20 Antibody - middle region
-
Séquence
- AAVYLREPQK TLFFVGDEYY SYDERKRKME KDYPKNTEEE FSGVNGQIDA
-
Homologie
- Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 92%
-
Attributs du produit
- This is a rabbit polyclonal antibody against MMP20. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human MMP20
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46497-100UG
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- prevent freeze-thaw cycles
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- MMP20 (Matrix Metalloproteinase 20 (MMP20))
-
Autre désignation
- MMP20
-
Sujet
-
Background Information: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP20 degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in the gene encoding MMP20, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta.
Gene Name: Matrix metallopeptidase 20
Alternative Symbols: AI2A2, MMP-20
Protein Name: Matrix metalloproteinase-20
-
Poids moléculaire
- 43kDa
-
ID gène
- 9313
-
NCBI Accession
- NP_004762
-
UniProt
- O60882
Antigène
-