DDOST anticorps (N-Term)

N° du produit ABIN2782672

L’anticorps anti-DDOST Polyclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de DDOST dans des échantillons provenant de Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin et Mouton. }

Aperçu rapide pour DDOST anticorps (N-Term) (ABIN2782672)

Antigène: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDOST est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DDOST anticorps

Épitope: N-Term

Séquence: SPSVEDFGGN INVETISAFI DGGGSVLVAA SSDIGDPLRE LGSECGIEFD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DDOST. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 456 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DDOST

Antigène: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Autre désignation: DDOST

Sujet: DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Alias Symbols: AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, OKSWcl45
Protein Interaction Partner: HUWE1, VAPB, UBC, FAF1, STAU1, ASB11, TRIM13, SUZ12, EED, CLN3, NXT1, SRSF11, FN1, ATF2, STT3B, MAGT1, ZMPSTE24, VDAC2, SSR4, SSR3, SLC25A3, ILF2, KRTCAP2, FBXO6, UBD, AMFR, AUP1, TMEM173, UNC93B1, MAPK6, HDAC5, AGO3, BRCC3, GSTK1, TMBIM4, PGRMC1, SAP18,
Protein Size: 456

Poids moléculaire: 46 kDa

ID gène: 1650

NCBI Accession: NM_005216, NP_005207

UniProt: Q5VWA5

Pathways: Cell RedoxHomeostasis