LMAN1 anticorps (N-Term)

N° du produit ABIN2782680

Cet anticorps Lapin Polyclonal détecte spécifiquement LMAN1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Lapin, Poisson zèbre (Danio rerio) et Cobaye.

Aperçu rapide pour LMAN1 anticorps (N-Term) (ABIN2782680)

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMAN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LMAN1 anticorps

Épitope: N-Term

Séquence: DPAVALPHRR FEYKYSFKGP HLVQSDGTVP FWAHAGNAIP SSDQIRVAPS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against LMAN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LMAN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 510 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LMAN1

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Autre désignation: LMAN1

Sujet: LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
Protein Interaction Partner: UBC, NEDD8, YIPF3, env, PIGS, TMED2, YBX1, HSP90AA1, HNRNPU, APP, UBXN6, RAB3GAP2, RAB3GAP1, COPE, TUBB4B, TUBB3, COPB2, VCP, DNAJC7, P4HB, HSPA8, HSPA1A, COPB1, COPA, BCAP29, BCAP31, HLA-A, CANX, ELAVL1, MCFD2, F8,
Protein Size: 510

Poids moléculaire: 54 kDa

ID gène: 3998

NCBI Accession: NM_005570, NP_005561

UniProt: P49257