LMAN1 anticorps (Middle Region)
-
- Antigène Voir toutes LMAN1 Anticorps
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
-
Épitope
- Middle Region
-
Reactivité
- Humain, Souris, Rat, Chien, Porc, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Cheval, Cobaye
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp LMAN1 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- DKKKEEFQKG HPDLQGQPAE EIFESVGDRE LRQVFEGQNR IHLEIKQLNR
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 90%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against LMAN1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human LMAN1
- Top Product
- Discover our top product LMAN1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 510 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
- Autre désignation
- LMAN1 (LMAN1 Produits)
- Synonymes
- anticorps ERGIC-53, anticorps ERGIC53, anticorps F5F8D, anticorps FMFD1, anticorps MCFD1, anticorps MR60, anticorps gp58, anticorps 2610020P13Rik, anticorps AI326273, anticorps AU043785, anticorps C730041J05, anticorps P58, anticorps p58, anticorps LMAN1, anticorps cpx-iii, anticorps cpxiii, anticorps lman1, anticorps wu:fc54c09, anticorps wu:fi36e01, anticorps Xp58, anticorps lman1-a, anticorps lectin, mannose binding 1, anticorps lectin, mannose-binding, 1, anticorps complexin 3, anticorps lectin, mannose binding 1 S homeolog, anticorps LMAN1, anticorps Lman1, anticorps cplx3, anticorps lman1, anticorps lman1.S
- Sujet
-
LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Alias Symbols: ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
Protein Interaction Partner: UBC, NEDD8, YIPF3, env, PIGS, TMED2, YBX1, HSP90AA1, HNRNPU, APP, UBXN6, RAB3GAP2, RAB3GAP1, COPE, TUBB4B, TUBB3, COPB2, VCP, DNAJC7, P4HB, HSPA8, HSPA1A, COPB1, COPA, BCAP29, BCAP31, HLA-A, CANX, ELAVL1, MCFD2, F8,
Protein Size: 510 - Poids moléculaire
- 54 kDa
- ID gène
- 3998
- NCBI Accession
- NM_005570, NP_005561
- UniProt
- P49257
-