MMP24 anticorps (Middle Region)

N° du produit ABIN2782729

L’anticorps anti-MMP24 Polyclonal Lapin est utilisé pour la détection de MMP24 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour MMP24 anticorps (Middle Region) (ABIN2782729)

Antigène: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP24 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MMP24 anticorps

Épitope: Middle Region

Fonction: MMP24 Antibody - middle region

Séquence: GSCLPREGID TALRWEPVGK TYFFKGERYW RYSEERRATD PGYPKPITVW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MMP24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MMP24

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46760-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MMP24

Antigène: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Autre désignation: MMP24

Sujet:

Background Information: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24.

Gene Name: Matrix metallopeptidase 24 (membrane-inserted)

Alternative Symbols: MMP25, MMP-24, MT5MMP, MTMMP5, MT-MMP5, MT5-MMP, MT-MMP 5

Protein Name: Matrix metalloproteinase-24

Poids moléculaire: 57kDa

ID gène: 10893

NCBI Accession: NP_006681

UniProt: Q9Y5R2