UGT1A4 anticorps (N-Term)

N° du produit ABIN2782758

Cet anticorps Lapin Polyclonal détecte spécifiquement UGT1A4 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour UGT1A4 anticorps (N-Term) (ABIN2782758)

Antigène: UGT1A4 (UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGT1A4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UGT1A4 anticorps

Épitope: N-Term

Fonction: UGT1A4 Antibody - N-terminal region

Séquence: VVLTPEVNMH IKEEKFFTLT AYAVPWTQKE FDRVTLGYTQ GFFETEHLLK

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UGT1A4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UGT1A4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115360

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur UGT1A4

Antigène: UGT1A4 (UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4))

Autre désignation: UGT1A4

Sujet:

Background Information: UGT1A4 is an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, hormones, and drugs, into water-soluble, excretable metabolites. This enzyme has some glucuronidase activity towards amines, steroids, and sapogenins. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter.

Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A4

Alternative Symbols: GNT1, UGT1, UDPGT, UGT1A, UGT1D, UGT-1A, UGT-1D, UGT1.1, UGT1.4, UGT1A1, HUG-BR2, UGT1-01, UGT1-04, UGT1A4S, hUG-BR1, UDPGT 1-4

Protein Name: UDP-glucuronosyltransferase 1-4

Poids moléculaire: 57kDa

ID gène: 54657

NCBI Accession: NP_009051

UniProt: P22310

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha